Wilson's Disease

Saturday, 23 March 2013

New Articles on WILSON DISEASE - SANDEEP S NAIR


Proc (Bayl Univ Med Cent). 2013 Apr;26(2):166-7.
Kayser-Fleischer rings of acute Wilson's disease.Mantas AM, Wells J, Trotter J


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Metab Brain Dis. 2013 Mar 22.
Influence of BDNF polymorphisms on Wilson's disease susceptibility and clinical course.

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Antioxid Redox Signal. 2013 Feb 6]
An Expanding Range of Functions for the Copper Chaperone/Antioxidant Protein Atox1.
Hatori Y, Lutsenko S.


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J Biol Chem. 2012 Aug 16; 19;287(43)
Molecular events initiating exit of a copper-transporting ATPase ATP7B from the trans-Golgi network.
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Metallomics. 2012 Jul;4(7):669-78.
A structural model of the copper ATPase ATP7B to facilitate analysis of Wilson disease-causing mutations and studies of the transport mechanism.


PLoS One. 2012 Jun 22;7(6)Urinary copper elevation in a mouse model of Wilson's disease is a regulated process to specifically decrease the hepatic copper load.

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Mutat Res. 2012 May 1;733(1-2):83-91.
The relationship of copper to DNA damage and damage prevention in humans.


Posted by Sandeep.S.Nair at 00:57
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Sandeep.S.Nair
PhD Scholar at AIIMS Delhi (Neurobiochemistry) with UGC SRF fellowship. NET qualified. Working on WILSON DISEASE
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Kayser-Fleischer rings

Kayser-Fleischer rings
copper accumulation in eyes

ATP7B

ATP7B
A mutation near the ATP binding site in the copper-regulating protein ATP7B causes Wilson disease

Followers

Kayser-Fleischer rings

Kayser-Fleischer rings
Kayser-Fleischer rings are present in almost all people with Wilson disease who show signs of neurologic damage but are present in only 50 percent of those with signs of liver damage alone.

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useful links

  • national digestive diseases control
  • medline plus
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